Terms and Conditions for the ORENCIA® (abatacept)
Co-pay for Subcutaneous and Intravenous Use
- Patients must have commercial insurance that pays for ORENCIA but does not cover the full cost. Co-pay assistance is not available if patient out-of-pocket expenses are $5 or less.
- Patients who have insurance coverage through a state or federal healthcare program, including Medicare, Medicaid, Medigap, CHAMPVA, Tricare, Veterans Affairs (VA), or Department of Defense (DoD), are not eligible. Patients who move from commercial to federal health insurance will no longer be eligible.
- Cash-paying patients are not eligible for co-pay assistance.
- Patients must be treated with ORENCIA for an FDA-approved indication.
- Patients or their guardian must be 18 years of age or older.
- Eligible patients with an activated co-pay card and a valid prescription may pay as little as $5 per 30-day supply; monthly, annual, and/or per-claim maximum program benefits may apply; max benefits and co-pay redemption methods may vary from patient to patient and over time, depending on the terms of a patient’s prescription drug plan and to ensure that the funds are used for the benefit of the patient, based on factors determined solely by Bristol Myers Squibb.
- Some prescription drug plans have established programs referred to as ‘co-pay maximizer’ programs. A co-pay maximizer program is one in which the amount of the patient’s out-of-pocket costs is adjusted to reflect the availability of support offered by a co-pay support program. Patients enrolled in co-pay maximizer programs may receive program benefits that vary over time to ensure the program funds are used for the benefit of the patient.
- For ORENCIA subcutaneous self-injection, the Co-pay Assistance Card must be presented at the pharmacy, along with a valid prescription for ORENCIA, at the time of purchase.
- The Card must be activated before use and includes 13 uses per calendar year. Patients will be evaluated for ongoing eligibility to continue enrollment in the program. In the event patients experience a change in insurance coverage or Bristol Myers Squibb makes changes to the copay assistance program, patients may be required to re-enroll into the program and provide updated insurance information to determine eligibility.
- For ORENCIA IV infusion, in order to receive Program benefits, the patient or provider must submit an Explanation of Benefits (EOB) form or a Remittance Advice (RA). The submitted form must include the name of the insurer, plan information, show that ORENCIA IV was the medication given, and be submitted within 180 days of the date of the EOB. The enrollment period is 1 calendar year. The Program may apply to out-of-pocket expenses that occurred within 180 days prior to the date of enrollment. Copay assistance payment will expire and will no longer be available if not used within 180 days of payment issuance.
- Program benefits are limited to the co-pay costs for ORENCIA that the patient receives as an outpatient. The Program will not cover the cost of any dosing procedure, any other healthcare provider service, supply charges, or other treatment costs.
- Program payments are for the benefit of the patient only.
- Patients, guardians, pharmacists, and healthcare providers may not seek reimbursement from health insurance or any third party for any part of the benefit received by the patient through this Program.
- Acceptance of this offer confirms that this offer is consistent with patient’s insurance. Patients, pharmacists, and healthcare providers must report the receipt of co-pay assistance benefits if required by the patient’s insurance provider.
- Offer valid only in the United States and Puerto Rico; void where prohibited by law, taxed, or restricted.
- Program benefits are nontransferable. This offer may not be combined with any other rebate/coupon, free trial, or similar offer.
- Co-pay cards are limited to 1 per patient and may not be sold, purchased, traded, or counterfeited.
- No membership fees.
- Program offer is not conditioned on any past, present, or future purchase, including additional doses or refills.
- The Program is not insurance.
- Bristol Myers Squibb reserves the right to rescind, revoke, or amend this offer at any time without notice. Other restrictions may apply.
Important Facts About ORENCIA® (abatacept)
This is a summary of important information that you need to know in order to take ORENCIA safely. Work with the healthcare provider to make the treatment suitable and safe for you or your loved one. Keep this information, so you can refer to it before and during your treatment.
Look out for the following icons as you read:
![]() |
Talk to your healthcare provider |
![]() |
Call a healthcare provider right away |
![]() |
Helpful information to remember |
What is ORENCIA?
ORENCIA (abatacept) is a prescription biologic medicine for:
Adult Rheumatoid Arthritis (RA)
ORENCIA is used to reduce signs and symptoms of moderate to severe Rheumatoid Arthritis (RA) in adults 18 years and older. Taking ORENCIA may prevent further damage to your bones and joints, and may help your ability to perform daily activities. ORENCIA may help those who are not getting the results they need with other medicines for RA.
In adults, ORENCIA may be used alone or with other RA treatments other than Janus kinase (JAK) inhibitors or biologic disease-modifying antirheumatic drugs (bDMARDs), such as tumor necrosis factor (TNF) antagonists (also called TNF-blockers). TNF-blockers are a type of RA medication, and include such treatments as Enbrel® (etanercept), Humira® (adalimumab), and Remicade® (infliximab).
Polyarticular Juvenile Idiopathic Arthritis (pJIA):
ORENCIA is used to reduce signs and symptoms of moderate to severe polyarticular JIA in patients 2 years of age and older. ORENCIA may be used alone or with methotrexate (MTX).
Psoriatic Arthritis (PsA)
ORENCIA is used to reduce signs and symptoms of active Psoriatic Arthritis in people 2 years of age and older. In adults, ORENCIA may be used alone or with other non-biologic PsA treatments. In children, ORENCIA can be used alone or with methotrexate.
ORENCIA should not be used with other strong medicines that affect the immune system, such as bDMARDs and JAK inhibitors.
![]() |
ORENCIA is for adults 18 years and older with moderate to severe RA. |
![]() |
ORENCIA is for patients 2 years of age and older with moderate to severe pJIA or active PsA. |
![]() |
ORENCIA should not be used with bDMARDs and JAK inhibitors. |
![]() |
ORENCIA has not been studied in children under 2 years of age. |
![]() |
ORENCIA has not been studied in children for uses other than pJIA. |
What should I discuss with my healthcare provider before starting ORENCIA?
![]() |
Talk to your healthcare provider about all of your medical conditions, including if:
|
![]() |
Tell your healthcare provider about all of your medical treatments, including if:
|
![]() |
Let your healthcare provider know if you are a woman who is:
|
What should I avoid while I am on ORENCIA?
ORENCIA and other medicines may affect each other, which could cause serious side effects. You should avoid taking ORENCIA with other biologics that may affect your immune system. Doing so may increase your chances of getting a serious infection.
![]() |
Tell your healthcare provider if you are taking other biologic medicines, such as:
|
![]() |
Talk to your healthcare provider before you begin to take anything new or if you have any changes to your medications during your treatment with ORENCIA. It is a good idea to keep an up-to-date list of all of your medicines, vitamins, and herbal supplements on hand to show your doctors and pharmacists. |
What are the possible side effects of ORENCIA?
This is a list of some of the possible side effects of ORENCIA for your reference.
![]() |
Talk to your healthcare provider about any side effect that may be bothering you. Your healthcare provider can work with you to manage side effects throughout your treatment. |
Serious side effects
Serious side effects are those that may require medical treatment or hospitalization, cause permanent damage, or be life-threatening or sometimes even fatal. Talk to your healthcare provider about any concerns you may have.
|
|
|
|
|
|
Most common side effects
The most common side effects of ORENCIA include:
|
In children and adolescents, other side effects may include:
|
These are not all of the possible side effects of ORENCIA. If you have any questions or want more information about side effects, ask your healthcare provider.
If you experience any side effects and would like to report them to the FDA, you can call 1-800-FDA-1088.
How will I receive ORENCIA?
ORENCIA is available in two forms, as intravenous (IV) infusions and as subcutaneous (SC) injections. Work with your healthcare provider to determine the right treatment plan for you or your child.
![]() |
ORENCIA IV infusion is given by a healthcare provider through a vein in your arm.
|
![]() |
ORENCIA SC injection is a shot that is given just under your skin. It is available as a prefilled syringe or ClickJect™ Autoinjector.
|